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Genetic leukoencephalopathies with unknown metabolic pathogenesis

✍ Scribed by A. Federico; A. Rufa; C. Battisti; S. Bianchi; E. Cardaioli; P. Da Pozzo; N. De Stefano; P. Formichi; F. Sicurelli; M. T. Dotti


Publisher
Springer Milan
Year
2001
Tongue
English
Weight
55 KB
Volume
22
Category
Article
ISSN
1590-1874

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A case of acute progressive multifocal leukoencephalopathy (PML) with hyper IgM syndrome 1 is reported. Viral DNA and VP1 protein of JC virus (JCV) and BK virus (BKV) were detected by immunohistochemistry, in situ hybridization, seminested polymerase chain (PCR) and PCR-restriction enzyme analysis.