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Genetic instability in cervical carcinoma

✍ Scribed by Min Zhao; Xin-xing Wu; Xiao-ping Qiu; Hui Li; Tian-li Dai; Yun Tan

Book ID
107466640
Publisher
Chinese Anti-Cancer Association
Year
2002
Tongue
English
Weight
423 KB
Volume
14
Category
Article
ISSN
1000-9604

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Microsatellite instability has been found preferentially in tumours associated with the hereditary non-polyposiscolorectal-cancer (HNPCC) syndrome. This phenotype, manifested as new alleles at microsatellite loci, and often the result of a defective mismatch-repair gene, is seen as allelic mobility