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Genetic heterogeneity of Mendelian susceptibility to mycobacterial infection

✍ Scribed by Rainer Döffinger; Frédéric Altare; Jean-Laurent Casanova

Book ID
108488900
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
328 KB
Volume
2
Category
Article
ISSN
1286-4579

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Mendelian susceptibility to mycobacteria
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✍ Frédéric Altare; Emmanuelle Jouanguy; Salma Lamhamedi; Rainer Döffinger; Alain F 📂 Article 📅 1998 🏛 Elsevier Science 🌐 English ⚖ 613 KB

Selective susceptibility to poorly pathogenic mycobacteria, such as bacille Calmette-GuBrin vaccine and environmental non-tuberculous mycobacteria, has long been suspected to be a mendelian disorder but its molecular basis has remained elusive. Recently, recessive mutations in the interferon-yrecept