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Genetic heterogeneity of Alport syndrome

✍ Scribed by Feingold, Josué; Bois, Etienne; Chompert, Agnès; Broyer, Michel; Gubler, Marie-Claire; Grünfeld, Jean-Pierre


Book ID
109880524
Publisher
Nature Publishing Group
Year
1985
Tongue
English
Weight
334 KB
Volume
27
Category
Article
ISSN
0085-2538

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Thirty one families with Alport syndrome including 3 families with associated syndromes were studied. The location of the COL4A5 gene, responsible for the Alport syndrome, was determined by linkage analysis with eight probes of the Xq arm and by a radiation hybrid panel. Concordant data indicated th