𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Genetic heterogeneity in mammalian specific-locus mutation systems

✍ Scribed by H. V. Malling

Publisher
John Wiley and Sons
Year
1995
Tongue
English
Weight
201 KB
Volume
26
Category
Article
ISSN
0893-6692

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

A biochemical specific locus mutation sy
A biochemical specific locus mutation system in mice
✍ H. V. Mailing; L. R. Valcovic πŸ“‚ Article πŸ“… 1977 πŸ› Springer-Verlag 🌐 English βš– 414 KB

Two mouse strains DBA/2J and C57BL/6J are heteromorphic with respect to the electrophoretic mobility of at least 8 enzymes and the beta-hemoglobin chain. The genotype of DBA/2J for these markers is: Es-1, Es-3, Gpd-1, Gpi-1, Id-1, Mod-1, Pmg-1, Dip-1 and Hbb; and of C57B1/6J: Es-1, Es-3, Gpd-1, Gpi-

The biochemical specific-locus test and
The biochemical specific-locus test and a new multiple-endpoint mutation detection system: Considerations for genetic risk assessment
✍ Dr. Susan E. Lewis πŸ“‚ Article πŸ“… 1991 πŸ› John Wiley and Sons 🌐 English βš– 375 KB

The importance of studying the generation of mutotions to human genetic risk is also dismutations in mouse germ cells is emphasized, cussed. Finally, the value of using multiple tests and the utility of the biochemical specific-locus for the study of in vivo germinal mutations is test in detecting g

BRCA1: A locus-specific β€œliaison” in gen
BRCA1: A locus-specific β€œliaison” in gene expression and genetic integrity
✍ Sarah Aiyar; Jian-long Sun; Rong Li πŸ“‚ Article πŸ“… 2005 πŸ› John Wiley and Sons 🌐 English βš– 185 KB

## Abstract Mutations in __BRCA1__ predominantly lead to elevated risks of breast and ovarian cancers. In contrast to the tissue‐specific nature of __BRCA1__tumors, the normal __BRCA1__ gene product functions in diverse nuclear events including transcription, DNA repair, and DNA damage checkpoint.