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Genetic heterogeneity in inborn errors of metabolism studied by enzyme analysis in single somatic cell hybrids

โœ Scribed by Galjaard, H. ;Hoogeveen, A. ;De Wit-Verbeek, H. A. ;Keijzer, W. ;Reuser, A. J. J.

Publisher
Springer
Year
1975
Tongue
English
Weight
196 KB
Volume
7
Category
Article
ISSN
0018-2214

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โœ Elinor Tolley; Ian Craig ๐Ÿ“‚ Article ๐Ÿ“… 1975 ๐Ÿ› Springer ๐ŸŒ English โš– 969 KB

Two major forms of fumarate hydratase have been resolved in extracts prepared from a wide variety of mammalian cells by electrophoresis. Fractionation experiments with human and mouse cells suggest that one form (the slower migrating) is localized in the mitochondria, whereas the other form is predo