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Genetic heterogeneity in Duchenne Dystrophy

โœ Scribed by Dr Craig L. Hyser; Michael Province; Robert C. Griggs; Jerry R. Mendell; Gerald M. Fenichel; Michael H. Brooke; J. Philip Miller; Renata Polakowska; Richard A. Doherty; Stephen Quirk


Publisher
John Wiley and Sons
Year
1987
Tongue
English
Weight
289 KB
Volume
22
Category
Article
ISSN
0364-5134

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โœ Zatz, Mayana ;Rabbi-Bortolini, Eliete ;Opitz, John M. ๐Ÿ“‚ Article ๐Ÿ“… 1987 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 76 KB ๐Ÿ‘ 1 views

We agree with Professor Emery that evidence is adding up suggesting heterogeneity of DMD at the molecular and cytogenetic levels Poyd and Buckle, 19861. However, this does not seem evident on clinical grounds. Our group of patients classified as mentally retarded [Bortolini and Zatz, 19861 all had

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In Duchenne muscular dystrophy (DMD), sphincter muscles tend to be clinically spared. However, urinary incontinence is occasionally reported, usually late in the course of the disease. We wished to determine the etiology of urinary dysfunction in patients with DMD. Seven boys with DMD and urinary dy