Genetic, environmental, and cellular factors in the pathogenesis of systemic lupus erythematosus

✍ Scribed by Alfred D. Steinberg; Elizabeth S. Raveche; Carl A. Laskin; Michael L. Miller; Robert T. Steinberg

• Publisher: John Wiley and Sons
• Year: 1982
• Tongue: English
• Weight: 997 KB
• Volume: 25
• Category: Article
• ISSN: 0004-3591
• DOI: 10.1002/art.1780250704

✦ Synopsis

We have i n v e s t i g a t e d t h e c e l l u l a r and g e n e t i c bas i s f o r autoimmunity i n s e v e r a l s t r a i n s o f mice t h a t develop disease resembling human systemic lupus e r ythematosus (SLE).

M u l t i p l e background genes a r e r es p o n s i b l e f o r disease i n NZB mice. A s i n g l e gene, =, Arthritis and Rheumatism, Vd. 25, So. 7 (July 1W)