Classification of rare missense substitu
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Sean V. Tavtigian; Graham B. Byrnes; David E. Goldgar; Alun Thomas
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Article
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2008
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John Wiley and Sons
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English
β 691 KB
## For the Mutation Pathogenicity Special Issue Many individually rare missense substitutions are encountered during deep resequencing of candidate susceptibility genes and clinical mutation screening of known susceptibility genes. BRCA1 and BRCA2 are among the most resequenced of all genes, and cl