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Genetic differences in the effects of competitive and non-competitive NMDA receptor antagonists on locomotor activity in mice

✍ Scribed by Sture Liljequist


Publisher
Springer
Year
1991
Tongue
English
Weight
673 KB
Volume
104
Category
Article
ISSN
0033-3158

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A competitive (NBQX) and a non-competitive (GYKI 52466) AMPA antagonist, and a competitive NMDA antagonist (D-CPPene) were tested against the development of kindling and against fully kindled seizures in amygdala-kindled rats. GYKI 52466, 10 mg/kg given i.p. 5 min prior to electrical stimulation in