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Genetic differences in a tail suspension test for evaluating antidepressant activity

✍ Scribed by Ramon Trullas; Barrington Jackson; Phil Skolnick

Publisher
Springer
Year
1989
Tongue
English
Weight
225 KB
Volume
99
Category
Article
ISSN
0033-3158

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Strain differences in response to drugs
Strain differences in response to drugs in the tail suspension test for antidepressant activity
✍ J. A. M. Heyden; E. Molewijk; B. Olivier πŸ“‚ Article πŸ“… 1987 πŸ› Springer 🌐 English βš– 321 KB

The effects of several types of antidepressants in a recently developed "behavioural despair" model, the tail-suspension test, are described. Drug effects on the automatically recorded duration of immobility and power of movements were measured in three strains of mice. Only in one strain (NMRI) did