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Genetic Determinants of Pediatric Inflammatory Bowel Disease: Is Age of Onset Genetically Determined?

✍ Scribed by Scherr, Rebecca; Essers, Jonah; Hakonarson, Hakon; Kugathasan, Subra

Book ID
120072048
Publisher
S. Karger AG
Year
2009
Tongue
English
Weight
116 KB
Volume
27
Category
Article
ISSN
0257-2753

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Nearly a third of inflammatory bowel disease (IBD) patients present in childhood or adolescence, with epidemiological and natural history studies clearly demonstrating a rising incidence in this population. Although early-onset disease has a distinct phenotype, such as more extensive disease at onse