Genetic deletion of regulator of G-protein signaling 4 (RGS4) rescues a subset of fragile X related phenotypes in the FMR1 knockout mouse

Failure to confirm genetic association b

Failure to confirm genetic association between schizophrenia and markers on chromosome 1q23.3 in the region of the gene encoding the regulator of G-protein signaling 4 protein (RGS4)

✍ Mie A. Rizig; Andrew McQuillin; Vinay Puri; Khalid Choudhury; Susmita Datta; Sri 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 68 KB 👁 3 views

## Abstract The chromosome 1q23.3 region, which includes the __RGS4__ gene has been implicated in genetic susceptibility to schizophrenia by two linkage studies with lod scores of 6.35 and 3.20 and with positive lod between 2.00 and 3.00 scores in several other studies. Reduced post mortem __RGS4__