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Genetic Defects of Intracellular-Membrane Transport

✍ Scribed by Epstein, Franklin H.; Olkkonen, Vesa M.; Ikonen, Elina


Book ID
125503666
Publisher
Massachusetts Medical Society
Year
2000
Tongue
English
Weight
501 KB
Volume
343
Category
Article
ISSN
0096-6762

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Copper is essential for life processes as cofactor for many vital cuproenzymes, yet it is extremely toxic in excess. Efficient mechanisms have been developed to recruit and deliver copper to enzymes and for excretion of surplus metal. Imbalance of copper homeostasis is manifested in two human illnes