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Genetic Contributions to Understanding Polyketide Synthases

✍ Scribed by Hopwood, David A.

Book ID
120207894
Publisher
American Chemical Society
Year
1997
Tongue
English
Weight
547 KB
Volume
97
Category
Article
ISSN
0009-2665

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## Abstract Multiple versions of the DEBS 1‐TE gene, which encodes a truncated bimodular polyketide synthase (PKS) derived from the erythromycin‐producing PKS, were created by replacing the DNA encoding the ketoreductase (KR) domain in the second extension module by either of two synthetic oligonuc