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Genetic changes in clinically organ-confined prostate cancer by comparative genomic hybridization

✍ Scribed by Wenting Fu; Lukas Bubendorf; Niels Willi; Holger Moch; Michael J Mihatsch; Guido Sauter; Thomas C Gasser


Book ID
117263145
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
320 KB
Volume
56
Category
Article
ISSN
0090-4295

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## Background: Germline mutations in recessive cancer predisposition genes are uncovered by somatic genetic deletions during tumor development. analysis of genetic changes in tumor tissues from patients with an inherited predisposition may therefore highlight regions of the genome containing suscep