Cystic fibrosis transmembrane conductance regulator (CFTR) mRNA transcripts isolated from both expressing and "non-expressing" cell types of normal individuals exhibit differential splicing to a variable extent in a region encoding the putative nucleotide binding fold of the CFTR polypeptide. Sequen
β¦ LIBER β¦
Genetic basis of variable exon 9 skipping in cystic fibrosis transmembrane conductance regulator mRNA
β Scribed by Chu, Chin-Shyan; Trapnell, Bruce C.; Curristin, Sheila; Cutting, Garry R.; Crystal, Ronald G.
- Book ID
- 109915128
- Publisher
- Nature Publishing Group
- Year
- 1993
- Tongue
- English
- Weight
- 589 KB
- Volume
- 3
- Category
- Article
- ISSN
- 1061-4036
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Lipoprotein lipase (LPL) catalyzes the hydrolysis of the core triacylglycerols of plasma very low density lipoproteins (VLDL) and chylomicrons . It thus controls a crucial step in the metabolism of triglycerides of exogenous and endogenous origin. Inherited LPL deficiency is clinically expressed as