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Genetic basis of potential therapeutic strategies for craniosynostosis

โœ Scribed by Heather Melville; Yingli Wang; Peter J. Taub; Ethylin Wang Jabs

Book ID
101450834
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
129 KB
Volume
152A
Category
Article
ISSN
1552-4825

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## Abstract Human engineered chromosomes (HECs) have several potential advantages over currently used vectors for gene therapy applications. Firstly, there is no upper size limit to DNA that can be cloned in these vectors. Secondly, their extrachromosomal nature ensures that introduced genes are ne