## Objective: To determine whether major histocompatibility complex (mhc) polymorphisms are associated with a good or poor response to infliximab therapy in patients with rheumatoid arthritis (ra). ## Methods: Seventy-eight infliximab-treated patients with ra were genotyped for hla-drb1, hla-dqa1
✦ LIBER ✦
Genetic association of the major histocompatibility complex with rheumatoid arthritis implicates two non-DRB1 loci
✍ Scribed by Charlotte Vignal; Aruna T. Bansal; David J. Balding; Michael H. Binks; Marion C. Dickson; Doug S. Montgomery; Anthony G. Wilson
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 274 KB
- Volume
- 60
- Category
- Article
- ISSN
- 0004-3591
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## Abstract ## Objective To identify additional variants in the major histocompatibility complex (MHC) region that independently contribute to risk in 2 disease subsets of rheumatoid arthritis (RA) defined according to the presence or absence of antibodies to citrullinated protein antigens (ACPAs)