Genetic aspects of H-Y antigen
β Scribed by Ulrich Wolf
- Publisher
- Springer
- Year
- 1981
- Tongue
- English
- Weight
- 449 KB
- Volume
- 58
- Category
- Article
- ISSN
- 0340-6717
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π SIMILAR VOLUMES
Anti-H-Y antiserum is generally obtained from female inbred mice or rats that have been hyperimmunized with syngeneic male cells. The specificity of such antiserum is defined by its reactivity for male but not female cells. A number of conventional serological assays have been used to measure that r
The H-Y antigen is a plasma membrane antigen involved in the organogenesis of the mammalian testis. Its expression on human cells is determined by a Y-linked gene. Phenotypic females affected by 46,XY gonadal dysgenesis (Swyer's syndrome) can be either H-Y-positive or H-Y-negative. In this paper we