Genetic approaches to study aging inDrosophila melanogaster
β Scribed by Luc Poirier; Laurent Seroude
- Book ID
- 106575333
- Publisher
- Springer Netherlands
- Year
- 2005
- Tongue
- English
- Weight
- 393 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0161-9152
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It has been shown repeatedly that numerous cumulative changes occur in chromosomes of D. melanogaster, as an effect of ageing which, especially in the homozygous state, significantly affect different fitness components of their carriers. It appears that the observed age-affected events are produced
Mutant strains sensitive and resistant to the drug 5-flourouracil (FU) have been isolated from the wild-type Pac strain of Drosophila melanogaster. The resistant strain, termed flu, is resistant to at least o.00035%FU (2.7x10(-4)M) in the food media and exhibits cross-resistance to 5-fluorodeoxyurid