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Genetic Approaches to Mammalian Nuclear Receptor Function in Yeast

โœ Scribed by Michael J. Garabedian

Book ID
115638530
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
724 KB
Volume
5
Category
Article
ISSN
1046-2023

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The expression of mammalian G protein coupled receptors (GPCRs) in S. cerevisiae provides a powerful assay system for functional analysis, ligand identiยฎcation and pharmaceutical screening. However, relatively few receptors have been coupled to the pheromone response pathway via the yeast G a , Gpa1