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Genetic approaches in mice to understand Rel/NF-κB and IκB function: transgenics and knockouts

✍ Scribed by Gerondakis, Steve; Grossmann, Mathis; Nakamura, Yukio; Pohl, Thomas; Grumont, Raelene


Book ID
110062598
Publisher
Nature Publishing Group
Year
1999
Tongue
English
Weight
155 KB
Volume
18
Category
Article
ISSN
0950-9232

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## Abstract The aim of this work was to evaluate the involvement of survival pathways in the response of Jurkat T leukaemic cells sensitive to the cytotoxic action of tumour necrosis factor (TNF)‐related apoptosis‐inducing ligand (TRAIL)/Apo2L. Jurkat T cells express TRAIL‐R2/DR5 and TRAIL‐R4/DcR2