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Genetic and epigenetic changes in primary metastatic and nonmetastatic colorectal cancer

✍ Scribed by Miranda, E; Destro, A; Malesci, A; Balladore, E; Bianchi, P; Baryshnikova, E; Franchi, G; Morenghi, E; Laghi, L; Gennari, L; Roncalli, M


Book ID
126692563
Publisher
Nature Publishing Group
Year
2006
Tongue
English
Weight
116 KB
Volume
95
Category
Article
ISSN
0007-0920

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## Abstract Microsatellite instability characterizes a sub‐set of sporadic colorectal cancers (CRCs) as well as CRCs from patients with hereditary non‐polyposis colorectal cancer (HNPCC). In order to clarify when the cells acquire a replication‐error phenotype (RER) during colorectal‐tumor progress