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Genetic and epigenetic alterations in the differential diagnosis of malignant melanoma and spitzoid lesion

✍ Scribed by M. Takata; J. Lin; S. Takayanagi; T. Suzuki; S. Ansai; T. Kimura; L. Cerroni; T. Saida


Book ID
108669474
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
196 KB
Volume
156
Category
Article
ISSN
0007-0963

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## Abstract The role of the __NF2__ gene in the development of meningiomas has recently been documented; inactivating mutations plus allelic loss at 22q, the site of this gene (at 22q12), have been identified in both sporadic and neurofibromatosis type 2–associated tumors. Although epigenetic inact