Genetic and clinical correlations of Xp21 muscular dystrophy
โ Scribed by K. M. D. Bushby
- Publisher
- Springer
- Year
- 1992
- Tongue
- English
- Weight
- 1007 KB
- Volume
- 15
- Category
- Article
- ISSN
- 0141-8955
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A DNA marker C7, localised Xp21.1-Xp21.3, has been studied in kindreds segregating for Duchenne muscular dystrophy (DMD) and Becker muscular dystrophy (BMD). In DMD families four crossovers were observed in 38 informative meioses between C7 and the DMD locus (theta = 0.12, z max = +2.72). In BMD fam
The association of congenital muscular dystrophy (CMD) with type I1 lissencephaly and ocular anomalies is found in Fukuyama CMD (FCMD), the Walker-Warburg syndrome (WWS), and muscle-eye-brain disease (MEBD). The classification of these disorders remains controversial. Between 1972 and 1992, we perfo