✦ LIBER ✦
Genetic analysis workshop III: Sib pair analyses to determine linkage groups and to order loci
✍ Scribed by R. C. Elston; B. J. B. Keats
- Publisher
- John Wiley and Sons
- Year
- 1985
- Tongue
- English
- Weight
- 124 KB
- Volume
- 2
- Category
- Article
- ISSN
- 0741-0395
No coin nor oath required. For personal study only.
✦ Synopsis
The methods proposed by Haseman and Elston [1972] were used to estimate the proportion of genes identical by descent shared by each sib pair at each locus. These estimates were then used as a basis for obtaining all possible locus-locus correlations. The 12 significant correlations (P < .01) and their rank order indicated the correct linkage groups and the order of the loci.