## Abstract E6βassociated protein (E6AP) is a cellular ubiquitin protein ligase that mediates ubiquitylation and degradation of tumor suppressor p53 in conjunction with the highβrisk human papillomavirus E6 protein. We previously reported that E6AP targets annexin A1 protein for ubiquitinβdependent
β¦ LIBER β¦
Genetic analysis of ubiquitin-dependent protein degradation
β Scribed by T. Sommer; W. Seufert
- Publisher
- Springer
- Year
- 1992
- Tongue
- English
- Weight
- 900 KB
- Volume
- 48
- Category
- Article
- ISSN
- 1420-682X
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One goal of plant genetic engineering is the manipulation of protein levels within crop plants. New insights into the ubiquitin-dependent proteolytic pathway provide potential novel ways of enhancing levels of desired proteins by synthesizing them as ubiquitin fusions, and reducing levels of undesir