A bacterial RNA polymerase mutant that r
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Lecocq, Jean-Pierre ;Dambly, Christine
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Article
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1976
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Springer
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English
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We describe a bacterial RNA polymerase mutation, rif 501, which confers rifampicin resistance and thermosensitivity to E. coli K 12. The purified RNA polymerase enzyme from rif 501 bacteria shows increased heatsensitivity in vitro at 51 degrees C. However, in vivo, at 42 degrees C the non-permissive