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Genetic analysis of the M RNA segment of Crimean-Congo hemorrhagic fever virus strains in Turkey

✍ Scribed by A. Ozdarendeli; K. Aydin; S. Tonbak; M. Aktas; K. Altay; I. Koksal; Y. Bolat; N. Dumanli; A. Kalkan


Publisher
Springer Vienna
Year
2007
Tongue
English
Weight
177 KB
Volume
153
Category
Article
ISSN
1432-8798

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Crimean-Congo hemorrhagic fever (CCHF) virus causes one of the most severe diseases in humans, with a mortality rate of up to 30%. It is transmitted to humans by the bite of hard ticks or by contact with blood or tissues from human patients or infected livestock. Balkan Peninsula is an endemic regio

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## Abstract Crimean‐Congo hemorrhagic fever (CCHF) is a potentially fatal disease caused by a tick‐borne virus in the family __Bunyavridae__. The disease occurs in parts of Africa, Asia, Middle East, and Eastern Europe. During recent years, an increasing number of human CCHF cases have been diagnos

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Alignment of Crimean-Congo hemorrhagic fever virus (CCHFV) L genome segment full-length sequences reveals an overall high level of conservation among strains, with greater than 90% of translated amino acid residues strictly conserved. However, a region of marked variability identified previously, co