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Genetic analysis of MAPT haplotype diversity in frontotemporal dementia

✍ Scribed by S.M. Laws; P. Friedrich; J. Diehl-Schmid; J. Müller; B. Ibach; J. Bäuml; T. Eisele; H. Förstl; A. Kurz; M. Riemenschneider

Book ID
116781095
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
103 KB
Volume
29
Category
Article
ISSN
0197-4580

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Tau is a multifunctional protein that was originally identified as a microtubule-associated protein. In patients diagnosed with frontotemporal dementia and parkinsonism linked to chromosome 17, mutations in the gene encoding tau (MAPT) have been identified that disrupt the normal binding of tau to t