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Genetic analysis of mammalian G-protein signalling

✍ Scribed by Offermanns, Stefan; Simon, Melvin I


Book ID
110061646
Publisher
Nature Publishing Group
Year
1998
Tongue
English
Weight
318 KB
Volume
17
Category
Article
ISSN
0950-9232

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G-protein-coupled receptors (GPCRs) play a crucial role in mediating e!ects of extracellular messengers in a wide variety of biological systems, comprising the largest gene superfamily at least in mammals. Mammalian GPCRs are broadly classi"ed into three families based on pharmacological properties