BACKGROUND. Increased risk of prostate cancer among men with a family history of the disease has been observed in several epidemiological studies, and family studies have identified hereditary prostate cancer characterized by early onset and autosomal dominant inheritance. METHODS. In this study, we
Genetic analysis of drinking behavior in World War II veteran twins
β Scribed by Dr. Dorit Carmelli; Andrew C. Heath; Dennis Robinette
- Publisher
- John Wiley and Sons
- Year
- 1993
- Tongue
- English
- Weight
- 692 KB
- Volume
- 10
- Category
- Article
- ISSN
- 0741-0395
No coin nor oath required. For personal study only.
β¦ Synopsis
Abstract
The objective of the present study was to investigate longitudinal changes in drinking behaviors of adult male twins and model these changes as a function of genetic and environmental influences. Alcohol data available for World War II veteran twins, first surveyed in 1967β69 and followed up during 1983β85, were used to examine components of variability in measures of alcohol consumption. Multivariate biometric analyses of these data indicated 1) longitudinal stability of drinking behaviors in this cohort, 2) a significant contribution of genetic factors to the observed stability that accounted for more than 80% of the stable variation in frequency and in quantity of alcohol consumed per drinking occasion, and 3) evidence for a significant contribution of shared environmental influences to drinking of specific beverages (e.g., wine). The implications of these results for issues of health in the elderly are considered. Β© 1993 WileyβLiss, Inc.
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