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Genetic alterations of chromosome band 9p21 – 22 in head and neck cancer are not restricted to p16INK4a

✍ Scribed by Waber, Pamela; Dlugosz, Sandra; Cheng, Qin-Chang; Truelson, John; Nisen, Perry D

Book ID
110060925
Publisher
Nature Publishing Group
Year
1997
Tongue
English
Weight
503 KB
Volume
15
Category
Article
ISSN
0950-9232

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The 9p21-23 chromosome region harbors a number of known and putative tumor-suppressor genes (TSGs). The best characterized gene in this area is p16 INK4A (CDKN2A). Alterations of its product have been observed in various malignancies, including non-small-cell lung carcinomas (NSCLCs). We earlier inv