Genetic alterations involved in the transition from well-differentiated to poorly differentiated and anaplastic thyroid carcinomas
โ Scribed by Yuri E. Nikiforov
- Book ID
- 111638529
- Publisher
- Springer US
- Year
- 2004
- Tongue
- English
- Weight
- 304 KB
- Volume
- 15
- Category
- Article
- ISSN
- 1046-3976
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## Abstract ## BACKGROUND The molecular pathogenesis of poorly differentiated endocrine carcinomas of the gastrointestinal tract (GI PDECs) remains unclear. It has been suggested that these lesions either originate from multipotent stem cells that also can serve as the origin of nonendocrine adeno
Background and Objectives: The importance of nodal involvement as a prognostic factor in differentiated carcinoma of the thyroid gland remains controversial. We therefore attempted to confirm the prognostic factors in differentiated thyroid carcinoma, with special reference to nodal status. Patients