Genetic Algorithms for Protein Folding Simulations
β Scribed by Ron Unger; John Moult
- Book ID
- 115625997
- Publisher
- Elsevier Science
- Year
- 1993
- Tongue
- English
- Weight
- 369 KB
- Volume
- 231
- Category
- Article
- ISSN
- 0022-2836
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π SIMILAR VOLUMES
Ab-initio folding simulations have been performed on three small proteins using a genetic algorithm-(GA-) based search method which operates on an all atom representation. Simulations were also performed on a number of small peptides expected to be independent folding units. The present genetic algo
We describe an algorithm to compute native structures of proteins from their primary sequences. The novel aspects of this method are: 1) The hydrophobic potential was set to be proportional to the nonpolar solvent accessible surface. To make computation feasible, we developed a new algorithm to comp