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Genes involved in pulmonary hypertension of mice with endothelial-specific ablation of guanylyl cyclase A

✍ Scribed by Werner, Franziska; Völker, Katharina; Scholz, Claus-Jürgen; Goebel, Margarethe; Seimetz, Michael; Kojonazarov, Baktybek; Schuh, Kai; Dahal, Bhola K; Schermuly, Ralph T; Oberwinkler, Heike; Gaßner, Birgit; Kuhn, Michaela


Book ID
121625532
Publisher
Springer (Biomed Central Ltd.)
Year
2013
Tongue
English
Weight
81 KB
Volume
14
Category
Article
ISSN
2050-6511

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## Abstract To dissect the tissue‐specific functions of atrial natriuretic peptide (ANP), we recently introduced loxP sites into the murine gene for its receptor, guanylyl cyclase‐A (GC‐A), by homologous recombination (tri‐lox __GC‐A__). For either smooth‐muscle or cardiomyocyte‐restricted deletion