Genes for interleukin-2 receptor β chain, interleukin-1 β, and schizophrenia: No evidence for the association or linkage

✍ Scribed by Tatsumi, Masahiko; Sasaki, Tsukasa; Sakai, Toshiyuki; Kamijima, Kunitoshi; Fukuda, Rimmei; Kunugi, Hiroshi; Hattori, Mineko; Nanko, Shinichiro

• Publisher: John Wiley and Sons
• Year: 1997
• Tongue: English
• Weight: 185 KB
• Volume: 74
• Category: Article
• ISSN: 0148-7299
• DOI: 10.1002/(sici)1096-8628(19970531)74:3<338::aid-ajmg17>3.0.co;2-p

✦ Synopsis

We studied a CA repeat polymorphism of the interleukin-2 receptor ␤ chain (IL-2RB) gene and a C/-514/T variation of the interleukin-1 ␤ (IL-1B) gene in Japanese schizophrenia patients. Both a case-control association study (54 patients and 54 controls) and a linkage study using six multiplex families (the number of the affected у4 in each family) were employed. No evidence for the association or the linkage was obtained either for the IL-2RB or IL-1B gene. Am.