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Genes and environment in susceptibility to visceral leishmaniasis

✍ Scribed by Sayda El-Safi; Musa M. Kheir; Bruno Bucheton; Laurent Argiro; Laurent Abel; Jacques Dereure; Jean Pierre Dedet; Alain Dessein

Book ID
116391673
Publisher
Elsevier Science
Year
2006
Tongue
French
Weight
519 KB
Volume
329
Category
Article
ISSN
1631-0691

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Visceral leishmaniasis (VL) or Kala-azar is a serious protozoan infectious disease caused by an obligate intracellular parasite. Cytokines have a major role in determining progression and severity of clinical manifestations in VL. We investigated polymorphisms in the TGFB1and IL8 genes, which are cy