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Generation of reactive oxygen species and NO• in the early phase of fibrosis: effect of interferon-γ

✍ Scribed by G. Svegliati-Baroni; A. de Jager-Krikken; S. Saccomanno; P.L.M. Jansen; A.M. Jezequel; H. Moshage

Book ID
118568299
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
175 KB
Volume
28
Category
Article
ISSN
0168-8278

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## Abstract The mechanism of induction of apoptosis by dolichyl phosphate (Dol‐P) was investigated in U937 cells. Studies using isolated mitochondria revealed that the respiratory complex II activity was almost completely inhibited by 20 µg/ml of Dol‐P but not by the same concentration of dolichol.