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Generation of particulate matter in large-volume parenteral containers

โœ Scribed by R. J. Whitlow; T. E. Needham; L. A. Luzzi

Publisher
John Wiley and Sons
Year
1974
Tongue
English
Weight
434 KB
Volume
63
Category
Article
ISSN
0022-3549

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โœฆ Synopsis

Polyvinyl chloride and glass large-volume parenteral containers were examined to determine the effects of agitation, storage, and additive handling on the generation of subvisual particulate matter. It was found that particles in flexible plastic containers can be generated by continuous shaking, with the maximum number of particles recorded after 30 hr of shaking. The par-

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