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Generation of nitric oxide by human neutrophils

✍ Scribed by Clifford D. Wright; Alexander Mu¨lsch; Rudi Busse; Hartmut Osswald


Book ID
115762485
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
404 KB
Volume
160
Category
Article
ISSN
0006-291X

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A chemiluminescence (CL) assay has been used to measure the reactive oxygen species (ROS)-generating capacity of phagocytes. Primed neutrophils produce ROS and nitric oxide (NO) upon induction of nitric oxide synthase (NOS) activity. NO and superoxide (O 2 À ) form peroxynitrite (ONOO À ), and emit