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Generation of mice with a conditional allele forIft172

✍ Scribed by Paul W. Howard; Tiffani L. Howard; Richard A. Maurer


Book ID
106550562
Publisher
Springer Netherlands
Year
2009
Tongue
English
Weight
354 KB
Volume
19
Category
Article
ISSN
0962-8819

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## Abstract Glucose‐6‐phosphatase‐α (G6Pase‐α or G6PC) catalyzes the hydrolysis of glucose‐6‐phosphate to glucose and is a key enzyme in interprandial glucose homeostasis. Mutations in the human __G6PC__ gene, expressed primarily in the liver, kidney, and intestine, cause glycogen storage disease T