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Generation of mice with a conditional allele for transforming growth factor beta 1 gene

✍ Scribed by Mohamad Azhar; Moying Yin; Ramireddy Bommireddy; John J. Duffy; Junqi Yang; Sharon A. Pawlowski; Gregory P Boivin; Sandra J. Engle; L.P. Sanford; Christina Grisham; Ram R. Singh; George F. Babcock; Thomas Doetschman

Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
853 KB
Volume
47
Category
Article
ISSN
1526-954X

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## Abstract Glucose‐6‐phosphatase‐α (G6Pase‐α or G6PC) catalyzes the hydrolysis of glucose‐6‐phosphate to glucose and is a key enzyme in interprandial glucose homeostasis. Mutations in the human __G6PC__ gene, expressed primarily in the liver, kidney, and intestine, cause glycogen storage disease T