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Generation of Hydroxyl Radical from Lipid Hydroperoxides Contained in Oxidatively Modified Low-Density Lipoprotein

โœ Scribed by K. Yagi; S. Komura; N. Ishida; N. Nagata; M. Kohno; N. Ohishi


Book ID
115572448
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
238 KB
Volume
190
Category
Article
ISSN
0006-291X

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A simple and sensitive method for the direct measurement of lipid peroxides in lipoprotein and liposomes is described. The method is based on the principle of the rapid peroxide-mediated oxidation of Fe2+ to Fe3+ under acidic conditions. The latter, in the presence of xylenol orange, forms a Fe(3+)-