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Generation of antigen-specific CD4+ T cell lines from naive precursors

✍ Scribed by Anita Mehta-Damani; Sergiusz Markowicz; Edgar G. Engleman


Publisher
John Wiley and Sons
Year
1995
Tongue
English
Weight
639 KB
Volume
25
Category
Article
ISSN
0014-2980

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Adoptive transfer of in vitro generated antigen-specific T cells has been successfully used to treat viral infections in immunodeficient patients. Therefore, methods for the rapid in vitro expansion of antigen-specific T cells are needed. Influenza virus efficiently infects dendritic cells, and pept