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Generation of anti-idiotypic reagents in the EGFRvIII tumor-associated antigen system

✍ Scribed by Carol J. Wikstrand, Vanessa R. Cole, Laura E. Crotty, John H. Sampson, Darell D. Bigner


Book ID
105966505
Publisher
Springer-Verlag
Year
2002
Tongue
English
Weight
352 KB
Volume
50
Category
Article
ISSN
0340-7004

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## Abstract Two monoclonal antibodies (KH‐1 and KH‐2) against a transplanted fibrosarcoma (KMT‐17) in WKA rats were produced by fusing a mouse myeloma (P~3~‐X63‐Ag8.653) with spleen cells from syngeneic rats hyperimmunized with KMT‐17. Both antibodies showed complement‐dependent cytotoxicity agains