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Generation of adult human induced pluripotent stem cells using nonviral minicircle DNA vectors

✍ Scribed by Narsinh, Kazim H; Jia, Fangjun; Robbins, Robert C; Kay, Mark A; Longaker, Michael T; Wu, Joseph C


Book ID
109946834
Publisher
Nature Publishing Group
Year
2010
Tongue
English
Weight
886 KB
Volume
6
Category
Article
ISSN
1750-2799

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With the advent of induced pluripotent stem cell (iPSC) technology, it is now feasible to generate iPSCs with a defined genotype or disease state. When coupled with direct differentiation to a defined lineage, such as hepatic endoderm (HE), iPSCs would revolutionize the way we study human liver biol