Generation of a nucleosome-free promoter region in SV40 does not require T-Antigen binding to site I

Differential regulation by SV40 t-antige

Differential regulation by SV40 t-antigen binding at site I defines two distinct classes of nucleosome-free promoter

✍ Kube, Dianne ;Milavetz, Barry 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 764 KB

Background: T-antigen binding site I has been shown previously to play a role in regulating the proportion of Simian Virus 40 (SV40) chromosomes containing a nuclease hypersensitive promoter region. In order to determine whether these changes in nuclease hypersensitivity were a result of changes in