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Generation of a De Novo Actin Pointed-End Binding Protein

✍ Scribed by Brawley, Crista M.; Uysal, Serdar; Rizk, Shahir; Luchniak, Anna; Kossiakoff, Anthony; Rock, Ronald S.

Book ID
119206978
Publisher
Biophysical Society
Year
2010
Tongue
English
Weight
31 KB
Volume
98
Category
Article
ISSN
0006-3495

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Binding of small molecules to cavity for
Binding of small molecules to cavity forming mutants of a de novo designed protein
✍ Aditi Das; Yinan Wei; Istvan Pelczer; Michael H. Hecht πŸ“‚ Article πŸ“… 2011 πŸ› Cold Spring Harbor Laboratory Press 🌐 English βš– 461 KB

## Abstract A central goal of protein design is to devise novel proteins for applications in biotechnology and medicine. Many applications, including those focused on sensing and catalysis will require proteins that recognize and bind to small molecules. Here, we show that stably folded α‐helical p